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In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination

Infection caused by the four serotypes of dengue virus (DENV-1-4) is a leading cause of mosquito-borne disease. Clinically-severe dengue disease is more common when secondary dengue infection occurs following prior infection with a heterologous dengue serotype. Other flaviviruses such as yellow feve...

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Detalles Bibliográficos
Autores principales: Whitehead, Stephen S., Durbin, Anna P., Pierce, Kristen K., Elwood, Dan, McElvany, Benjamin D., Fraser, Ellen A., Carmolli, Marya P., Tibery, Cecilia M., Hynes, Noreen A., Jo, Matthew, Lovchik, Janece M., Larsson, Catherine J., Doty, Elena A., Dickson, Dorothy M., Luke, Catherine J., Subbarao, Kanta, Diehl, Sean A., Kirkpatrick, Beth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436874/
https://www.ncbi.nlm.nih.gov/pubmed/28481883
http://dx.doi.org/10.1371/journal.pntd.0005584