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ROS regulation of axonal mitochondrial transport is mediated by Ca(2+) and JNK in Drosophila

Mitochondria perform critical functions including aerobic ATP production and calcium (Ca(2+)) homeostasis, but are also a major source of reactive oxygen species (ROS) production. To maintain cellular function and survival in neurons, mitochondria are transported along axons, and accumulate in regio...

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Detalles Bibliográficos
Autores principales: Liao, Pin-Chao, Tandarich, Lauren C., Hollenbeck, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436889/
https://www.ncbi.nlm.nih.gov/pubmed/28542430
http://dx.doi.org/10.1371/journal.pone.0178105