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ROS regulation of axonal mitochondrial transport is mediated by Ca(2+) and JNK in Drosophila
Mitochondria perform critical functions including aerobic ATP production and calcium (Ca(2+)) homeostasis, but are also a major source of reactive oxygen species (ROS) production. To maintain cellular function and survival in neurons, mitochondria are transported along axons, and accumulate in regio...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436889/ https://www.ncbi.nlm.nih.gov/pubmed/28542430 http://dx.doi.org/10.1371/journal.pone.0178105 |