MUC1-C ACTIVATES BMI1 IN HUMAN CANCER CELLS

BMI1 is a component of the PRC1 complex that is overexpressed in breast and other cancers, and promotes self-renewal of cancer stem-like cells. The oncogenic mucin 1 (MUC1) C-terminal (MUC1-C) subunit is similarly overexpressed in human carcinoma cells and has been linked to their self-renewal. Ther...

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Detalles Bibliográficos
Autores principales: Hiraki, Masayuki, Maeda, Takahiro, Bouillez, Audrey, Alam, Maroof, Tagde, Ashujit, Hinohara, Kunihiko, Suzuki, Yozo, Markert, Tahireh, Miyo, Masaaki, Komura, Kazumasa, Ahmad, Rehan, Rajabi, Hasan, Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436937/
https://www.ncbi.nlm.nih.gov/pubmed/27893710
http://dx.doi.org/10.1038/onc.2016.439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436937/
https://www.ncbi.nlm.nih.gov/pubmed/27893710
http://dx.doi.org/10.1038/onc.2016.439

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