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MUC1-C ACTIVATES BMI1 IN HUMAN CANCER CELLS

BMI1 is a component of the PRC1 complex that is overexpressed in breast and other cancers, and promotes self-renewal of cancer stem-like cells. The oncogenic mucin 1 (MUC1) C-terminal (MUC1-C) subunit is similarly overexpressed in human carcinoma cells and has been linked to their self-renewal. Ther...

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Detalles Bibliográficos
Autores principales:	Hiraki, Masayuki, Maeda, Takahiro, Bouillez, Audrey, Alam, Maroof, Tagde, Ashujit, Hinohara, Kunihiko, Suzuki, Yozo, Markert, Tahireh, Miyo, Masaaki, Komura, Kazumasa, Ahmad, Rehan, Rajabi, Hasan, Kufe, Donald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436937/ https://www.ncbi.nlm.nih.gov/pubmed/27893710 http://dx.doi.org/10.1038/onc.2016.439

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