Identification of MYST3 as a novel epigenetic activator of ERα frequently amplified in breast cancer

Estrogen receptor α (ERα) is a master driver of a vast majority of breast cancers. Breast cancer cells often develop resistance to endocrine therapy via restoration of the ERα activity through survival pathways. Thus identifying the epigenetic activator of ERα that can be targeted to block ERα gene...

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Detalles Bibliográficos
Autores principales: Yu, L, Liang, Y, Cao, X, Wang, X, Gao, H, Lin, S-Y, Schiff, R, Wang, X-S, Li, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436938/
https://www.ncbi.nlm.nih.gov/pubmed/27893709
http://dx.doi.org/10.1038/onc.2016.433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436938/
https://www.ncbi.nlm.nih.gov/pubmed/27893709
http://dx.doi.org/10.1038/onc.2016.433

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