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COOPERATION AMONG HETEROGENEOUS PROSTATE CANCER CELLS IN THE BONE METASTATIC NICHE
The growth of disseminated tumor cells (DTCs) into metastatic lesions depends on the establishment of a favorable microenvironment in the stroma of the target organs. Here we show that mice treated with anakinra, an antagonist of the IL-1β receptor (IL-1R), or harboring a targeted deletion of IL-1R...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436952/ https://www.ncbi.nlm.nih.gov/pubmed/27991924 http://dx.doi.org/10.1038/onc.2016.436 |