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COOPERATION AMONG HETEROGENEOUS PROSTATE CANCER CELLS IN THE BONE METASTATIC NICHE

The growth of disseminated tumor cells (DTCs) into metastatic lesions depends on the establishment of a favorable microenvironment in the stroma of the target organs. Here we show that mice treated with anakinra, an antagonist of the IL-1β receptor (IL-1R), or harboring a targeted deletion of IL-1R...

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Detalles Bibliográficos
Autores principales: Shahriari, Kristina, Shen, Fei, Worrede-Mahdi, Asurayya, Liu, Qingxin, Gong, Yulan, Garcia, Fernando U., Fatatis, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436952/
https://www.ncbi.nlm.nih.gov/pubmed/27991924
http://dx.doi.org/10.1038/onc.2016.436