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Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer

In a previous study, we detected a significant association between phosphoserine aminotransferase 1 (PSAT1) hyper-methylation and mRNA levels to outcome to tamoxifen treatment in recurrent disease. We here aimed to study the association of PSAT1 protein levels to outcome upon tamoxifen treatment and...

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Detalles Bibliográficos
Autores principales: De Marchi, Tommaso, Timmermans, Mieke A., Sieuwerts, Anieta M., Smid, Marcel, Look, Maxime P., Grebenchtchikov, Nicolai, Sweep, Fred C. G. J., Smits, Jan G., Magdolen, Viktor, van Deurzen, Carolien H. M., Foekens, John A., Umar, Arzu, Martens, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437008/
https://www.ncbi.nlm.nih.gov/pubmed/28522855
http://dx.doi.org/10.1038/s41598-017-02296-w