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Lipoxygenase 2 from Cyanothece sp. controls dioxygen insertion by steric shielding and substrate fixation

The biological function of lipoxygenases depends on the regio and stereo specific formation of fatty acid-derived hydroperoxides and different concepts exist to explain the mechanism that directs dioxygen to a specific carbon atom within the substrate. Here, we report the 1.8 Å resolution crystal st...

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Detalles Bibliográficos
Autores principales: Newie, Julia, Neumann, Piotr, Werner, Martin, Mata, Ricardo A., Ficner, Ralf, Feussner, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437038/
https://www.ncbi.nlm.nih.gov/pubmed/28522865
http://dx.doi.org/10.1038/s41598-017-02153-w