A Molecular Basis for Selective Antagonist Destabilization of Dopamine D(3) Receptor Quaternary Organization

The dopamine D(3) receptor (D(3)R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a substantial proportion of the receptor was prese...

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Detalles Bibliográficos
Autores principales: Marsango, Sara, Caltabiano, Gianluigi, Jiménez-Rosés, Mireia, Millan, Mark J., Pediani, John D., Ward, Richard J., Milligan, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437050/
https://www.ncbi.nlm.nih.gov/pubmed/28522847
http://dx.doi.org/10.1038/s41598-017-02249-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437050/
https://www.ncbi.nlm.nih.gov/pubmed/28522847
http://dx.doi.org/10.1038/s41598-017-02249-3

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