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A Molecular Basis for Selective Antagonist Destabilization of Dopamine D(3) Receptor Quaternary Organization
The dopamine D(3) receptor (D(3)R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a substantial proportion of the receptor was prese...
Autores principales: | Marsango, Sara, Caltabiano, Gianluigi, Jiménez-Rosés, Mireia, Millan, Mark J., Pediani, John D., Ward, Richard J., Milligan, Graeme |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437050/ https://www.ncbi.nlm.nih.gov/pubmed/28522847 http://dx.doi.org/10.1038/s41598-017-02249-3 |
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