Myosin heavy chain and cardiac troponin T damage is associated with impaired myofibrillar ATPase activity contributing to sarcomeric dysfunction in Ca(2+)-paradox rat hearts

This study aimed to explore the potential contribution of myofibrils to contractile dysfunction in Ca(2+)-paradox hearts. Isolated rat hearts were perfused with Krebs–Henseleit solution (Control), followed by Ca(2+)-depletion, and then Ca(2+)-repletion after Ca(2+)-depletion (Ca(2+)-paradox) by Lang...

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Detalles Bibliográficos
Autores principales: Kovács, Árpád, Kalász, Judit, Pásztor, Enikő T., Tóth, Attila, Papp, Zoltán, Dhalla, Naranjan S., Barta, Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437149/
https://www.ncbi.nlm.nih.gov/pubmed/28213770
http://dx.doi.org/10.1007/s11010-017-2954-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437149/
https://www.ncbi.nlm.nih.gov/pubmed/28213770
http://dx.doi.org/10.1007/s11010-017-2954-8

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