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The Connected Steady State Model and the Interdependence of the CSF Proteome and CSF Flow Characteristics

Here we show that the hydrodynamic radii-dependent entry of blood proteins into cerebrospinal fluid (CSF) can best be modeled with a diffusional system of consecutive interdependent steady states between barrier-restricted molecular flux and bulk flow of CSF. The connected steady state model fits pr...

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Detalles Bibliográficos
Autores principales: Metzger, Fabian, Mischek, Daniel, Stoffers, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437178/
https://www.ncbi.nlm.nih.gov/pubmed/28579938
http://dx.doi.org/10.3389/fnins.2017.00241