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Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation

Leukaemia cells that are resistant to conventional therapies are thought to reside in protective niches. Here, we describe light-inducible polymeric retinoic acid (RA)-containing nanoparticles (NPs) with the capacity to accumulate in the cytoplasm of leukaemia cells for several days and release thei...

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Detalles Bibliográficos
Autores principales: Boto, Carlos, Quartin, Emanuel, Cai, Yijun, Martín-Lorenzo, Alberto, Cenador, María Begoña García, Pinto, Sandra, Gupta, Rajeev, Enver, Tariq, Sánchez-García, Isidro, Hong, Dengli, Pires das Neves, Ricardo, Ferreira, Lino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437273/
https://www.ncbi.nlm.nih.gov/pubmed/28492285
http://dx.doi.org/10.1038/ncomms15204