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Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation
Leukaemia cells that are resistant to conventional therapies are thought to reside in protective niches. Here, we describe light-inducible polymeric retinoic acid (RA)-containing nanoparticles (NPs) with the capacity to accumulate in the cytoplasm of leukaemia cells for several days and release thei...
Autores principales: | Boto, Carlos, Quartin, Emanuel, Cai, Yijun, Martín-Lorenzo, Alberto, Cenador, María Begoña García, Pinto, Sandra, Gupta, Rajeev, Enver, Tariq, Sánchez-García, Isidro, Hong, Dengli, Pires das Neves, Ricardo, Ferreira, Lino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437273/ https://www.ncbi.nlm.nih.gov/pubmed/28492285 http://dx.doi.org/10.1038/ncomms15204 |
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