Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain

RNA polymerase II contains a repetitive, intrinsically disordered, C-terminal domain (CTD) composed of heptads of the consensus sequence YSPTSPS. The CTD is heavily phosphorylated and serves as a scaffold, interacting with factors involved in transcription initiation, elongation and termination, RNA...

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Detalles Bibliográficos
Autores principales: Portz, Bede, Lu, Feiyue, Gibbs, Eric B., Mayfield, Joshua E., Rachel Mehaffey, M., Zhang, Yan Jessie, Brodbelt, Jennifer S., Showalter, Scott A., Gilmour, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437306/
https://www.ncbi.nlm.nih.gov/pubmed/28497792
http://dx.doi.org/10.1038/ncomms15231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437306/
https://www.ncbi.nlm.nih.gov/pubmed/28497792
http://dx.doi.org/10.1038/ncomms15231

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