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LAV-BPIFB4 isoform modulates eNOS signalling through Ca(2+)/PKC-alpha-dependent mechanism
AIMS: Ageing is associated with impairment of endothelial nitric oxide synthase (eNOS) and progressive reduction in endothelial function. A genetic study on long-living individuals—who are characterized by delays in ageing and in the onset of cardiovascular disease—previously revealed I229V (rs20703...
Autores principales: | Spinelli, Chiara Carmela, Carrizzo, Albino, Ferrario, Anna, Villa, Francesco, Damato, Antonio, Ambrosio, Mariateresa, Madonna, Michele, Frati, Giacomo, Fucile, Sergio, Sciaccaluga, Miriam, Capunzo, Mario, Calì, Gaetano, Milanesi, Luciano, Maciag, Anna, Puca, Annibale Alessandro, Vecchione, Carmine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437365/ https://www.ncbi.nlm.nih.gov/pubmed/28419216 http://dx.doi.org/10.1093/cvr/cvx072 |
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