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Low expression of CD39 and CD73 genes in centenarians compared with octogenarians

Ageing involves a progressive decline of the body’s regulatory systems including immune system. Adenosine regulates immune function by interaction with its receptors, mainly adenosine A2A receptor, present on the surface of immune cells. Furthermore, cellular response to this nucleoside is highly de...

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Detalles Bibliográficos
Autores principales: Crooke, Almudena, Martínez-Henández, Juan, Martínez-López, Joaquín, Cruz-Jentoft, Alfonso, Huete-Toral, Fernando, Pintor, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437401/
https://www.ncbi.nlm.nih.gov/pubmed/28529533
http://dx.doi.org/10.1186/s12979-017-0094-3