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Low expression of CD39 and CD73 genes in centenarians compared with octogenarians
Ageing involves a progressive decline of the body’s regulatory systems including immune system. Adenosine regulates immune function by interaction with its receptors, mainly adenosine A2A receptor, present on the surface of immune cells. Furthermore, cellular response to this nucleoside is highly de...
Autores principales: | Crooke, Almudena, Martínez-Henández, Juan, Martínez-López, Joaquín, Cruz-Jentoft, Alfonso, Huete-Toral, Fernando, Pintor, Jesús |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437401/ https://www.ncbi.nlm.nih.gov/pubmed/28529533 http://dx.doi.org/10.1186/s12979-017-0094-3 |
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