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Frequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinoma

Primary hepatocellular carcinoma (HCC) mainly develops in subjects chronically infected with hepatitis B (HBV) and C (HCV) viruses through a multistep process characterized by the accumulation of genetic alterations in the human genome. Nucleotide changes in coding regions (i.e. TP53, CTNNB1, ARID1A...

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Detalles Bibliográficos
Autores principales: Pezzuto, Francesca, Buonaguro, Luigi, Buonaguro, Franco M., Tornesello, Maria Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437489/
https://www.ncbi.nlm.nih.gov/pubmed/28529542
http://dx.doi.org/10.1186/s13027-017-0138-5