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Modeling the dynamics of mouse iron body distribution: hepcidin is necessary but not sufficient

BACKGROUND: Iron is an essential element of most living organisms but is a dangerous substance when poorly liganded in solution. The hormone hepcidin regulates the export of iron from tissues to the plasma contributing to iron homeostasis and also restricting its availability to infectious agents. D...

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Detalles Bibliográficos
Autores principales: Parmar, Jignesh H., Davis, Grey, Shevchuk, Hope, Mendes, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437513/
https://www.ncbi.nlm.nih.gov/pubmed/28521769
http://dx.doi.org/10.1186/s12918-017-0431-3