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Disrupted-in-Schizophrenia-1 is essential for normal hypothalamic-pituitary-interrenal (HPI) axis function

Psychiatric disorders arise due to an interplay of genetic and environmental factors, including stress. Studies in rodents have shown that mutants for Disrupted-In-Schizophrenia-1 (DISC1), a well-accepted genetic risk factor for mental illness, display abnormal behaviours in response to stress, but...

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Detalles Bibliográficos
Autores principales: Eachus, Helen, Bright, Charlotte, Cunliffe, Vincent T., Placzek, Marysia, Wood, Jonathan D., Watt, Penelope J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437527/
https://www.ncbi.nlm.nih.gov/pubmed/28334933
http://dx.doi.org/10.1093/hmg/ddx076