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The effect of hypoxia on the lipidome of recombinant Pichia pastoris

BACKGROUND: Cultivation of recombinant Pichia pastoris (Komagataella sp.) under hypoxic conditions has a strong positive effect on specific productivity when the glycolytic GAP promoter is used for recombinant protein expression, mainly due to upregulation of glycolytic conditions. In addition, tran...

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Detalles Bibliográficos
Autores principales: Adelantado, Núria, Tarazona, Pablo, Grillitsch, Karlheinz, García-Ortega, Xavier, Monforte, Sergi, Valero, Francisco, Feussner, Ivo, Daum, Günther, Ferrer, Pau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437588/
https://www.ncbi.nlm.nih.gov/pubmed/28526017
http://dx.doi.org/10.1186/s12934-017-0699-4