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The effect of hypoxia on the lipidome of recombinant Pichia pastoris
BACKGROUND: Cultivation of recombinant Pichia pastoris (Komagataella sp.) under hypoxic conditions has a strong positive effect on specific productivity when the glycolytic GAP promoter is used for recombinant protein expression, mainly due to upregulation of glycolytic conditions. In addition, tran...
Autores principales: | Adelantado, Núria, Tarazona, Pablo, Grillitsch, Karlheinz, García-Ortega, Xavier, Monforte, Sergi, Valero, Francisco, Feussner, Ivo, Daum, Günther, Ferrer, Pau |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437588/ https://www.ncbi.nlm.nih.gov/pubmed/28526017 http://dx.doi.org/10.1186/s12934-017-0699-4 |
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