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Analysis of the DNA methylation level of cancer-related genes in colorectal cancer and the surrounding normal mucosa

BACKGROUND: Two molecular pathways promote the development of colorectal cancer (CRC). One is termed “microsatellite stable” (MSS) whereas the other is characterized by “microsatellite instability” (MSI or MIN). In addition, the CpG island methylation phenotype is known to be an important alteration...

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Detalles Bibliográficos
Autores principales: Sugai, Tamotsu, Yoshida, Masakazu, Eizuka, Makoto, Uesugii, Noriyuki, Habano, Wataru, Otsuka, Kouki, Sasaki, Akira, Yamamoto, Eiichiro, Matsumoto, Takayuki, Suzuki, Hiromu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437595/
https://www.ncbi.nlm.nih.gov/pubmed/28533824
http://dx.doi.org/10.1186/s13148-017-0352-4