Survival rates of homozygotic Tp53 knockout rats as a tool for preclinical assessment of cancer prevention and treatment

BACKGROUND: The gene that encodes tumor protein p53, Tp53, is mutated or silenced in most human cancers and is recognized as one of the most important cancer drivers. Homozygotic Tp53 knockout mice, which develop lethal cancers early in their lives, are already used in cancer prevention studies, and...

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Detalles Bibliográficos
Autores principales: Strzemecki, Damian, Guzowska, Magdalena, Grieb, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437597/
https://www.ncbi.nlm.nih.gov/pubmed/28536640
http://dx.doi.org/10.1186/s11658-017-0039-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437597/
https://www.ncbi.nlm.nih.gov/pubmed/28536640
http://dx.doi.org/10.1186/s11658-017-0039-z

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