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Immunogenicity and immunomodulatory effects of the human chondrocytes, hChonJ

BACKGROUND: Invossa™ (TissueGene-C) is a cell and gene therapy for osteoarthritis. It is composed of primary human chondrocytes (hChonJ cells) and irradiated human chondrocytes modified to express TGF-β1 (hChonJb#7 cells). The hChonJ cells were isolated from a polydactyly donor, and TGF-β1 cDNA was...

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Detalles Bibliográficos
Autores principales: Lim, Chae-Lyul, Lee, Yeon-Ju, Cho, Jong-Ho, Choi, Heonsik, Lee, Bumsup, Lee, Myung Chul, Kim, Sujeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437658/
https://www.ncbi.nlm.nih.gov/pubmed/28521800
http://dx.doi.org/10.1186/s12891-017-1547-8