High-Resolution RNA Maps Suggest Common Principles of Splicing and Polyadenylation Regulation by TDP-43

Many RNA-binding proteins (RBPs) regulate both alternative exons and poly(A) site selection. To understand their regulatory principles, we developed expressRNA, a web platform encompassing computational tools for integration of iCLIP and RNA motif analyses with RNA-seq and 3′ mRNA sequencing. This r...

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Detalles Bibliográficos
Autores principales: Rot, Gregor, Wang, Zhen, Huppertz, Ina, Modic, Miha, Lenče, Tina, Hallegger, Martina, Haberman, Nejc, Curk, Tomaž, von Mering, Christian, Ule, Jernej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437728/
https://www.ncbi.nlm.nih.gov/pubmed/28467899
http://dx.doi.org/10.1016/j.celrep.2017.04.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437728/
https://www.ncbi.nlm.nih.gov/pubmed/28467899
http://dx.doi.org/10.1016/j.celrep.2017.04.028

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