The elephant shark methylome reveals conservation of epigenetic regulation across jawed vertebrates

Background: Methylation of CG dinucleotides constitutes a critical system of epigenetic memory in bony vertebrates, where it modulates gene expression and suppresses transposon activity. The genomes of studied vertebrates are pervasively hypermethylated, with the exception of regulatory elements suc...

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Detalles Bibliográficos
Autores principales: Peat, Julian R., Ortega-Recalde, Oscar, Kardailsky, Olga, Hore, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437953/
https://www.ncbi.nlm.nih.gov/pubmed/28580133
http://dx.doi.org/10.12688/f1000research.11281.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437953/
https://www.ncbi.nlm.nih.gov/pubmed/28580133
http://dx.doi.org/10.12688/f1000research.11281.1

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