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The elephant shark methylome reveals conservation of epigenetic regulation across jawed vertebrates
Background: Methylation of CG dinucleotides constitutes a critical system of epigenetic memory in bony vertebrates, where it modulates gene expression and suppresses transposon activity. The genomes of studied vertebrates are pervasively hypermethylated, with the exception of regulatory elements suc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000Research
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437953/ https://www.ncbi.nlm.nih.gov/pubmed/28580133 http://dx.doi.org/10.12688/f1000research.11281.1 |