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Non-canonical targets play an important role in microRNA stability control mechanisms

MicroRNAs (miRNAs) regulate gene expression by guiding the Argonaute (Ago)-containing RNA-induced silencing complex (RISC) to specific target mRNA molecules. It is well established that miRNAs are stabilized by Ago proteins, but the molecular features that trigger miRNA destabilization from Ago prot...

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Detalles Bibliográficos
Autores principales: Park, June Hyun, Shin, Chanseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437957/
https://www.ncbi.nlm.nih.gov/pubmed/28228216
http://dx.doi.org/10.5483/BMBRep.2017.50.4.029