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Longevity regulation by NMD-mediated mRNA quality control

Proper maintenance of biological components is crucial for longevity and healthy aging. Although the role of homeostatic maintenance systems for DNA and protein in longevity is established, it remains largely unknown for RNA. In our recent work, we show that nonsense-mediated mRNA decay (NMD) promot...

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Detalles Bibliográficos
Autores principales: Son, Heehwa G., Lee, Seung-Jae V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437958/
https://www.ncbi.nlm.nih.gov/pubmed/28288699
http://dx.doi.org/10.5483/BMBRep.2017.50.4.045