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Rare damaging variants in DNA repair and cell cycle pathways are associated with hippocampal and cognitive dysfunction: a combined genetic imaging study in first-episode treatment-naive patients with schizophrenia

Schizophrenia is a complex neurodevelopmental disorder where changes in both hippocampus and memory-related cognitive functions are central. However, the exact relationship between neurodevelopmental-genetic factors and hippocampal-cognitive dysfunction remains unclear. The general aim of our study...

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Detalles Bibliográficos
Autores principales: Yang, Z, Li, M, Hu, X, Xiang, B, Deng, W, Wang, Q, Wang, Y, Zhao, L, Ma, X, Sham, P C, Northoff, G, Li, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438026/
https://www.ncbi.nlm.nih.gov/pubmed/28195569
http://dx.doi.org/10.1038/tp.2016.291