Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan

Lifespan is a trait of enormous personal interest. Research into the biological basis of human lifespan, however, is hampered by the long time to death. Using a novel approach of regressing (272,081) parental lifespans beyond age 40 years on participant genotype in a new large data set (UK Biobank),...

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Peter K., Fischer, Krista, Schraut, Katharina E., Campbell, Harry, Esko, Tõnu, Wilson, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438072/
https://www.ncbi.nlm.nih.gov/pubmed/27029810
http://dx.doi.org/10.1038/ncomms11174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438072/
https://www.ncbi.nlm.nih.gov/pubmed/27029810
http://dx.doi.org/10.1038/ncomms11174

Ejemplares similares