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Granulocyte colony-stimulating factor blockade enables dexamethasone to inhibit lipopolysaccharide-induced murine lung neutrophils

Glucocorticoids promote neutrophilic inflammation, the mechanisms of which are poorly characterized. Using a lipopolysaccharide (LPS)-induced acute murine lung injury model, we determined the role of granulocyte colony-stimulating factor (G-CSF) in mouse lung neutrophil numbers in the absence and pr...

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Detalles Bibliográficos
Autores principales: Banuelos, Jesus, Cao, Yun, Shin, Soon Cheon, Bochner, Bruce S., Avila, Pedro, Li, Shihong, Jiang, Xin, Lingen, Mark W., Schleimer, Robert P., Lu, Nick Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438114/
https://www.ncbi.nlm.nih.gov/pubmed/28542361
http://dx.doi.org/10.1371/journal.pone.0177884