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In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression

Xenobiotic activation of the aryl hydrocarbon receptor (AHR) by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) prevents the proper formation of craniofacial cartilage and the heart in developing zebrafish. Downstream molecular targets responsible for AHR-dependent adverse effects remain largely unknown;...

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Detalles Bibliográficos
Autores principales: Garcia, Gloria R., Goodale, Britton C., Wiley, Michelle W., La Du, Jane K., Hendrix, David A., Tanguay, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438132/
https://www.ncbi.nlm.nih.gov/pubmed/28385905
http://dx.doi.org/10.1124/mol.117.108233