Widespread position-specific conservation of synonymous rare codons within coding sequences

Synonymous rare codons are considered to be sub-optimal for gene expression because they are translated more slowly than common codons. Yet surprisingly, many protein coding sequences include large clusters of synonymous rare codons. Rare codons at the 5’ terminus of coding sequences have been shown...

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Detalles Bibliográficos
Autores principales: Chaney, Julie L., Steele, Aaron, Carmichael, Rory, Rodriguez, Anabel, Specht, Alicia T., Ngo, Kim, Li, Jun, Emrich, Scott, Clark, Patricia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438181/
https://www.ncbi.nlm.nih.gov/pubmed/28475588
http://dx.doi.org/10.1371/journal.pcbi.1005531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438181/
https://www.ncbi.nlm.nih.gov/pubmed/28475588
http://dx.doi.org/10.1371/journal.pcbi.1005531

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