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Hairless-binding deficient Suppressor of Hairless alleles reveal Su(H) protein levels are dependent on complex formation with Hairless

Cell fate choices during metazoan development are driven by the highly conserved Notch signalling pathway. Notch receptor activation results in release of the Notch intracellular domain (NICD) that acts as transcriptional co-activator of the DNA-binding protein CSL. In the absence of signal, a repre...

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Detalles Bibliográficos
Autores principales: Praxenthaler, Heiko, Nagel, Anja C., Schulz, Adriana, Zimmermann, Mirjam, Meier, Markus, Schmid, Hannes, Preiss, Anette, Maier, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438185/
https://www.ncbi.nlm.nih.gov/pubmed/28475577
http://dx.doi.org/10.1371/journal.pgen.1006774