Cargando…
Hairless-binding deficient Suppressor of Hairless alleles reveal Su(H) protein levels are dependent on complex formation with Hairless
Cell fate choices during metazoan development are driven by the highly conserved Notch signalling pathway. Notch receptor activation results in release of the Notch intracellular domain (NICD) that acts as transcriptional co-activator of the DNA-binding protein CSL. In the absence of signal, a repre...
Autores principales: | Praxenthaler, Heiko, Nagel, Anja C., Schulz, Adriana, Zimmermann, Mirjam, Meier, Markus, Schmid, Hannes, Preiss, Anette, Maier, Dieter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438185/ https://www.ncbi.nlm.nih.gov/pubmed/28475577 http://dx.doi.org/10.1371/journal.pgen.1006774 |
Ejemplares similares
-
Generation of New Hairless Alleles by Genomic Engineering at the Hairless Locus in Drosophila melanogaster
por: Praxenthaler, Heiko, et al.
Publicado: (2015) -
Complex genetic interactions of novel Suppressor of Hairless alleles deficient in co-repressor binding
por: Preiss, Anette, et al.
Publicado: (2018) -
Gain of Function Notch Phenotypes Associated with Ectopic Expression of the Su(H) C-Terminal Domain Illustrate Separability of Notch and Hairless-Mediated Activities
por: Maier, Dieter, et al.
Publicado: (2013) -
Molecular Analysis of the Notch Repressor-Complex in Drosophila: Characterization of Potential Hairless Binding Sites on Suppressor of Hairless
por: Kurth, Patricia, et al.
Publicado: (2011) -
Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster
por: Yuan, Zhenyu, et al.
Publicado: (2016)