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A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination

Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to DNA double-strand breaks (DSBs) that will be preferentially repaired by homologous recombination when the sister chromatid is available. The Rrm3 helicase is a replisome component...

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Detalles Bibliográficos
Autores principales: Muñoz-Galván, Sandra, García-Rubio, María, Ortega, Pedro, Ruiz, Jose F., Jimeno, Sonia, Pardo, Benjamin, Gómez-González, Belén, Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438189/
https://www.ncbi.nlm.nih.gov/pubmed/28475600
http://dx.doi.org/10.1371/journal.pgen.1006781