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A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to DNA double-strand breaks (DSBs) that will be preferentially repaired by homologous recombination when the sister chromatid is available. The Rrm3 helicase is a replisome component...
Autores principales: | Muñoz-Galván, Sandra, García-Rubio, María, Ortega, Pedro, Ruiz, Jose F., Jimeno, Sonia, Pardo, Benjamin, Gómez-González, Belén, Aguilera, Andrés |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438189/ https://www.ncbi.nlm.nih.gov/pubmed/28475600 http://dx.doi.org/10.1371/journal.pgen.1006781 |
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