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Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53
The transcription factor p53 is at the core of a built-in tumor suppression system that responds to varying degrees of stress input and is deregulated in most human cancers. Befitting its role in maintaining cellular fitness and fidelity, p53 regulates an appropriate set of target genes in response...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438217/ https://www.ncbi.nlm.nih.gov/pubmed/28560349 http://dx.doi.org/10.1126/sciadv.1603204 |