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Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53

The transcription factor p53 is at the core of a built-in tumor suppression system that responds to varying degrees of stress input and is deregulated in most human cancers. Befitting its role in maintaining cellular fitness and fidelity, p53 regulates an appropriate set of target genes in response...

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Detalles Bibliográficos
Autores principales: Miyamoto, Takafumi, Lo, Paulisally Hau Yi, Saichi, Naomi, Ueda, Koji, Hirata, Makoto, Tanikawa, Chizu, Matsuda, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438217/
https://www.ncbi.nlm.nih.gov/pubmed/28560349
http://dx.doi.org/10.1126/sciadv.1603204