Cargando…
Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53
The transcription factor p53 is at the core of a built-in tumor suppression system that responds to varying degrees of stress input and is deregulated in most human cancers. Befitting its role in maintaining cellular fitness and fidelity, p53 regulates an appropriate set of target genes in response...
Autores principales: | Miyamoto, Takafumi, Lo, Paulisally Hau Yi, Saichi, Naomi, Ueda, Koji, Hirata, Makoto, Tanikawa, Chizu, Matsuda, Koichi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438217/ https://www.ncbi.nlm.nih.gov/pubmed/28560349 http://dx.doi.org/10.1126/sciadv.1603204 |
Ejemplares similares
-
Identification of a novel p53 target, COL17A1, that inhibits breast cancer cell migration and invasion
por: Yodsurang, Varalee, et al.
Publicado: (2017) -
Cystatin C as a p53‐inducible apoptotic mediator that regulates cathepsin L activity
por: Mori, Jinichi, et al.
Publicado: (2016) -
Regulation of iron homeostasis by the p53-ISCU pathway
por: Funauchi, Yuki, et al.
Publicado: (2015) -
INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4
por: Liu, Yu-Yu, et al.
Publicado: (2019) -
EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis()
por: Mori, Jinichi, et al.
Publicado: (2017)