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Induction of senescence in primary glioblastoma cells by serum and TGFβ

Glioblastoma is the most common type of adult brain tumour and has a median survival after diagnosis of a little more than a year. Glioblastomas have a high frequency of mutations in the TERT promoter and CDKN2A locus that are expected to render them resistant to both replicative and oncogene-induce...

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Detalles Bibliográficos
Autores principales: Kumar, Ritesh, Gont, Alexander, Perkins, Theodore J., Hanson, Jennifer E. L., Lorimer, Ian A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438350/
https://www.ncbi.nlm.nih.gov/pubmed/28526854
http://dx.doi.org/10.1038/s41598-017-02380-1