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Induction of senescence in primary glioblastoma cells by serum and TGFβ
Glioblastoma is the most common type of adult brain tumour and has a median survival after diagnosis of a little more than a year. Glioblastomas have a high frequency of mutations in the TERT promoter and CDKN2A locus that are expected to render them resistant to both replicative and oncogene-induce...
Autores principales: | Kumar, Ritesh, Gont, Alexander, Perkins, Theodore J., Hanson, Jennifer E. L., Lorimer, Ian A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438350/ https://www.ncbi.nlm.nih.gov/pubmed/28526854 http://dx.doi.org/10.1038/s41598-017-02380-1 |
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