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Gut homeostasis and regulatory T cell induction depend on molecular chaperone gp96 in CD11c(+) cells

The intestinal immunity and tolerance are orchestrated by both the innate and the adaptive immune system. Intestinal professional antigen presenting cells (pAPCs) recognize and respond to the gut microbiota through multiple pattern-recognition receptors, including TLRs and NLRs. How gut pAPCs mainta...

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Detalles Bibliográficos
Autores principales: Hua, Yunpeng, Yang, Yi, Sun, Shaoli, Iwanowycz, Stephen, Westwater, Caroline, Reizis, Boris, Li, Zihai, Liu, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438351/
https://www.ncbi.nlm.nih.gov/pubmed/28526855
http://dx.doi.org/10.1038/s41598-017-02415-7