Thioflavin T fluoresces as excimer in highly concentrated aqueous solutions and as monomer being incorporated in amyloid fibrils

Fluorescence of thioflavin T (ThT) is a proven tool for amyloid fibrils study. The correct model of ThT binding to fibrils is crucial to clarify amyloid fibrils structure and mechanism of their formation. Although there are convincing evidences that ThT has molecular rotor nature, implying it’s bind...

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Detalles Bibliográficos
Autores principales: Sulatskaya, Anna I., Lavysh, Andrey V., Maskevich, Alexander A., Kuznetsova, Irina M., Turoverov, Konstantin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438369/
https://www.ncbi.nlm.nih.gov/pubmed/28526838
http://dx.doi.org/10.1038/s41598-017-02237-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438369/
https://www.ncbi.nlm.nih.gov/pubmed/28526838
http://dx.doi.org/10.1038/s41598-017-02237-7

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