Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism

Major depressive disorder is a complex and common mental disease, for which the pathology has not been elucidated. The purpose of this study is to provide knowledge about the importance of mitochondrial dysfunction, dysregulated lipid metabolism and inflammation. Mitochondrial carnitine palmitoyl tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Mørkholt, Anne Skøttrup, Wiborg, Ove, Nieland, Jette G. K., Nielsen, Søren, Nieland, John Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438386/
https://www.ncbi.nlm.nih.gov/pubmed/28526869
http://dx.doi.org/10.1038/s41598-017-02343-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438386/
https://www.ncbi.nlm.nih.gov/pubmed/28526869
http://dx.doi.org/10.1038/s41598-017-02343-6

Ejemplares similares