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Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism
Major depressive disorder is a complex and common mental disease, for which the pathology has not been elucidated. The purpose of this study is to provide knowledge about the importance of mitochondrial dysfunction, dysregulated lipid metabolism and inflammation. Mitochondrial carnitine palmitoyl tr...
Autores principales: | Mørkholt, Anne Skøttrup, Wiborg, Ove, Nieland, Jette G. K., Nielsen, Søren, Nieland, John Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438386/ https://www.ncbi.nlm.nih.gov/pubmed/28526869 http://dx.doi.org/10.1038/s41598-017-02343-6 |
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